Women's Services Encyclopedia
The coagulation profile is a blood test that measures the interval of time for several stages of the blood clotting cycle. Values are reported
in seconds (the time it takes for the blood to clot). Also referred to as the Prothrombin Time (PT) and Partial Thromboplastin
these tests give the doctor information pertaining to liver function (the liver produces clotting factors needed to make blood
Conditions where the coagulation profile is of importance include:
- Assessment of liver function
- Pre-operative screening test, before any surgery
- Following anticoagulation in those patients taking oral anticoagulants (Warfarin)
- Establishing coagulation status for patients needing future anticoagulation therapy
- Testing coagulation in patients with a disease known to interfere with normal coagulation
The coagulation profile is performed from a venipuncture specimen.
Approximate Normal Values:
- Prothrombin Time (PT) = 11.0 to 12.5 seconds (results vary with regard to controls). Elevated above normal in patients
taking blood thinners (Warfarin) or in those who are vitamin K deficient. Therapeutic anticoagulation is often approximately 1.5
times the normal prothrombin time (or a PT of about 17-18).
- Partial Thromboplastin Time (PTT) = 25 to 50 seconds (results may vary with regard to controls). Elevated in some
cases of severe liver disease (cirrhosis).
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